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    Home » Christina Applegate ‘Back at Square One’ After MS Misdiagnosis

    Christina Applegate ‘Back at Square One’ After MS Misdiagnosis

    October 20, 2026 Entertainment Vids 1 Min Read
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    Christina Applegate breaks down in tears as she reveals doctors have told her she may not have multiple sclerosis, despite being diagnosed with the disease in 2021. In an emotional return to her ‘MeSsy’ podcast, the actress opens up about the devastating uncertainty surrounding her health, her debilitating symptoms and the toll they’ve taken on her career, independence and mental health. Dr. Marwa Kaisey chats with ET’s Nichelle Turner to explain why MS misdiagnoses can happen and what might be next for Applegate.

    More from Entertainment Tonight: https://www.youtube.com/channel/UCdtXPiqI2cLorKaPrfpKc4g?sub_confirmation=1

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